Class Notes at Lehigh University

BIOE 324 22119 Lecture 10 Textured and Porous Materials Advantages of PorousTextured Materials Promote tissue ingrowth, improve implant fixation Minimize fibrotic encapsulation Promote angiogenesis Drug elutionminimize inf...

BIOE 324 21419 Lecture 8 Structure of Native Collagen > 10 different forms, tissue specific Type I: skin, tendon, bone Type II: cartilage Type III: blood vessel wall and skin Type IV: basement membrane (separate epithelial...

BIOE 324 21219 Lecture 7 Hydrogels Contact lenses, Drug delivery Tissue engineering scaffold Artificial skin Water swollen, cross-linked polymers Covalent bondassociation bond (H-bond or VDW interations)crystallites Homopo...

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BIOE 324 12919 Lecture 3 Mechanical Property of Interest Modulus (since higher E materials correlate with higher strength) Yield stressstress at onset of plastic deformation Ultimate (tensile) strength (UTS)peak of stresss...

BIOE 324 13119 Lecture 4 Surfaces in Biomaterials -dictates many biological responses The unusual properties of surfaces and interfaces are due to unbalanced intermolecular interaction forces (or energies across the surfac...

BIOE 324 12419 Lecture 2 Materials Selection Material properties vary greatly between material classes and even within a material class. Design of engineering components require the use of materials for which certain prope...

BIOE 324 2519 Lecture 5 Types of Polymers Natural polymers Plant: cellulose, alginate, natural rubber Animal: tissue based heart valves, heparin, DNA, protein Synthetic polymers Hydrophobic, non-water absorbing Polar Water...

BIOE 324 12219 Lecture 1 What are biomaterials? A (nonviable) materials used in a (medical) device, intended to interact with biological systems Types of Materials Used Engineered materials Polymer Metal Ceramic Carbon Com...

BIOE 324 2719 Lecture 6 Molecular Weight Measurement Polymer Synthesis Free radical polymerization: addition Unsaturated monomers 3 reaction stages: initiation, propagation and termination Free radical from thermal decompo...

12519 BIOE 226 Lecture 1 Class Schedule Class meetings 23 - Responsible bioengineering design and development. Case study 1. Class meetings 45 - Humans and Animals in Research. Case study 2. Class meetings 67 - Human augme...

2119 BIOE 226 Lecture 2 Moral development and engineers 1. Concern for wider society: helping people, future generations 2. Concern about peerscommunity: professionalism, best practices, everyday ethical conduct 3. Avoid p...