BISC 130 Lecture Notes - Lecture 8: Dna Polymerase I, Okazaki Fragments, Helicase
Document Summary
Dna is genetic material, a polymer of 4 nucleotides, phosphodiester covalent bonds hold together the sides, hydrogen bonds hold together the nucleotides in the middle, bases stacked 3" end to 5" end, resulting in one end of the. Dna replication: semi-conservative- one new strand formed from using the old one as a template, dna replication needs a template, enzymes to link nucleotides together, and building blocks (nucleotides) Steps of dna replication: dna helicase breaks down hydrogen bonds to make single strands of dna. Dna: the final dna fragment connects to first rna. It cannot be replicated: photolyase- breaks the bond apart using visible light; only repair thymine dimers, excision repair- complex of enzymes cuts out a chunk of. Dna that includes the damaged dna (ucr a, b, c: dna polymerase replaces the dna and dna ligase attaches the end to the original strand.