BISC 320 Lecture Notes - Lecture 21: Fetal Hemoglobin, Respiratory Pigment, Deep Diving
19 Oct 2017
School
Department
Course
Professor
Document Summary
Their blood is highly sensitive to pathogens and will clot if only a few bacteria are present. They are caught, bled in facilities, and then released. The process usually doesn"t kill them: chlorocruorin and erythrocruorin, some annelids (marine worms, large iron/heme proteins; green or red. Cooperativity in oxygen binding: respiratory pigments display hyperbolic (no cooperativity) or sigmoid (cooperativity) equilibrium curves depending on whether they exhibit cooperativity in o2 binding, with no cooperativity, the respiratory pigment holds onto oxygen at lower oxygen concentrations. Once it is bound to the pigment, it is difficult to remove it. Partial pressure of oxygen in the lungs, around 100 torr, helps o2 to bind to hemoglobin. This makes hemoglobin good for circulating oxygen and myoglobin good for storing oxygen in the tissues. Once circulating o2 in the blood is used up, then oxygen will be released from myoglobin: mechanism of hemoglobin: deoxyhemoglobin in the lungs has conformational mobility it is not rigid.
