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Lecture 2

BIOL 1201 Lecture Notes - Lecture 2: Cancer, Oncogene, Start Codon

Biological Sciences
Course Code
BIOL 1201
Moroney, James

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Chapter 18
Gene Expression
1. Sections 18.1, 18.2, and 18.5
2. Tryptophan
a. When the trp concentration is too high, transcription stops
i. When the trp repressor is closed/full, transcription stops
b. When the trp concentration becomes too low, it falls o$ and
transcription continues
i. When the trp repressor is open/empty, transcription
c. Only blocks when trp is bound Promoter – region on the DNA
where RNA polymerase binds to begin transcription
d. Operator – region on the DNA where repressor proteins can bind
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