18.095 Lecture Notes - Lecture 5: Positive And Negative Syndrome Scale, Aripiprazole, Bernoulli Distribution
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To be approved by the fda, the clinical trials must demonstrate that the drug is more performant than the placebo. In principle, we can extrapolate as much as we want but the bigger the population the larger the sample we have access to. It may be impossible or too costly to query the entire population. Population: voters on the day of an election. Consider the iowa republican caucuses in which there were 121,501 voting republicans. Is 530 a large enough number of voters to survey in order to determine the poll"s front runner. In class we asked 5 students to measure (in cm) the following. Before releasing abilify in 2002, otsuka ran clinical trials to measure the ef cacy of the drug among other things such as side effects. Population of interest: all potential future consumers of abilify. This is an abstract population, unlike the voter example. The study was run on 414 patients, measuring some criterion called panss.
