C_S_D 4430 Lecture Notes - Lecture 12: Reuptake, Acetylcholine
Document Summary
Synaptic transmission, continued 2: postsynaptic processes: integration and summation. Refers to the reduction of hundreds of synaptic inputs to ap"s. It takes many synaptic sites respectively active for a substantial time to excite most postsynaptic cells to fire an ap. This lets cells be controlled by input from many neurons. Refers to the summing of individual sources of synaptic input simplest form of synaptic integration in the ns. Affects the size of postsynaptic potentials an thus the chances of the membrane reaching the ap threshold. The adding together of psp"s generated simultaneously at many different synapses (adding across space-diff synapses: temporal summation. When receptors slowly lose responsiveness to an agonist when it is continuously present for a while. Diffusion of the nt away from the synaptic cleft. Breakdown of the nt into an unusable form. Re-uptake of the nt, usually into the presynaptic cell. Acetylcholine: (ach) the nt of the neuromuscular involved in both excitatory* and inhibitory* transmission.
