HLTH-307 Lecture Notes - Lecture 9: Diabetes Insipidus, Glycated Hemoglobin, Metformin

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Synthesis, storage, and release of: insulin. Beta cells (islets of langerhans, pancreatic islets: glucagon. Anterior pituitary: hyposecretion (too little secretion of growth hormone) Pituitary dwarfism: hypersecretion (too much of growth hormone) Posterior pituitary: hyposecretion (of antidiuretic hormone) Hypothyroidism (not secreting enough thyroid hormone: s/s: unexplained weight gain, hair loss, swollen, fatigue, slower thinking, infertility, cold. Hyperthyroidism (grave"s disease: s/s: nervous, irritable, weight loss, hot, sweating, bulging eyes, insomnia. Diseases of the adrenal cortex: hypoadrenalism. Underproduction of cortisol (stress hormone), aldosterone, and androgens (addison"s disease) s/s: weight loss, fatigue, hyperpigmentation of skin, gi distress, fainting and hypotension: hyperadrenalism. Overproduction of cortisol (cushing"s syndrome) s/s: moon- shaped, buffalo hump, hypertension, weight gain, large abdomen. Diabetes mellitus: type 1 diabetes mellitus (t1dm, type 2 diabetes mellitus, gestational diabetes. Formerly called juvenile diabetes, due to onset usually in childhood. Auto-immune condition characterized by little or no insulin production. Risk factors: genetics, family history, exposure to certain viral infections,

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