BIO 320 Lecture Notes - Lecture 3: Angiogenesis, Thromboxane, Sepsis
Document Summary
Cellular accumulations (infiltration: water, lipids, glycogen, proteins, pigments. Lipofuscin (uptake of parts of organelle: breakdown of organelles. Indicator of wear and tear: used to determine age of an organ. Metastatic: hypercalcemia, see in hyperthyroidism is a thyroid issue. Requires that they are able to eliminate foreign invaders and threats: ex: infectious pathogens, damaged tissues. I(cid:374)fla(cid:373)(cid:373)atio(cid:374) is the (cid:271)ody"s a(cid:374)s(cid:449)er a(cid:374)d its prote(cid:272)ti(cid:448)e (cid:373)e(cid:272)ha(cid:374)is(cid:373) I(cid:374)fla(cid:373)(cid:373)atio(cid:374) is defi(cid:374)ed (cid:271)y i(cid:373)(cid:373)u(cid:374)ologists as part of our (cid:862)i(cid:374)(cid:374)ate i(cid:373)(cid:373)u(cid:374)ity(cid:863) Look for foreign invaders and recruit others and move to chemical signal. Increased oncotic pressure in ecf: extra cellular fluid will leak. Hydrostatic pressure = blood pressure - out. Osmotic press= return pressure back into blood stream- pushing back in. Kinis (cytokines: tnf-a, il-1 (different chemical signals) Vascular endothelial growth factor (vegf: endothelium cells are responsive towards. In circulation monocyte is round- macrophage becomes bumpy. Tethering slightly attach and let go. Angiogenesis: development of blood vessels from old vessels.
