BIO 375 Lecture Notes - Lecture 6: Dna Virus, Viremia, Immunodeficiency
Document Summary
Chicken pox: dsdna, human reservoir, transmission most frequent airborne but in can also be transmitted by direct contact, fewer skin vesicles in children in adults. Incubation 4-7 days done by 2-3 weeks: virus causes cells to fuse doubling the virus load, one of the most infectious viruses, moves around rapidly. Human herpes virus 3 (varicella) extremely contagious from respiratory fluid and lesion fluid. Less serious in children very serious in adults. Skin lesions filled with clear fluid very itchy. After a few days they encrust and drop off, but can leave scars, especially with scratching and secondary infection. Lesion distribution is centripetal more in the center of the body, fewer in extremities. Patients contagious until all lesions have crusted over. Varicella virus enters host through respiratory system. The virus attaches to respiratory mucosa, invades, and enters bloodstream. Virus causes adjacent cells to fuse and lyse. Virus can enter sensory nerves at lesion locations.
