ACMS10145 Lecture 10: Chapter 10

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blushdinosaur832

19 Feb 2019

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Applied & Comp Math and Stats

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ACMS10145

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All

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Document Summary

In chapters 8 and 9 we showed how to develop confidence intervals and conduct hypothesis tests for situations involving a single population mean and a single population proportion. In sections 10. 1-10. 3 we continue our discussion of statistical inference by showing how confidence intervals and hypothesis tests can be developed for situations involving two populations, when the difference between the two population means is of prime importance. 10. 1 inferences about the difference between two population means: 1 and 2. 1 and a simple random sample of size n2 from population 2: let 1 x equal the mean of sample 1 and x equal the mean of sample 2. 2: the point estimator of the difference between the means of the populations 1 and. 1: (1- )*100% confidence interval of the difference 1 - 2: x. Example: homestyle sells furniture at two stores: one is located in the inner city and the other is located in a suburban shopping center.

Related Questions

QUESTION 1What is the purpose of post hoc tests? Under what circumstances are post hoc tests not needed or appropriate?

a. Under what circumstances is ANOVA a more appropriate statistical technique to use than a t test for independent samples? Please provide an example(s) to support your answer. (2 marks)

b. (2 marks)

c. In testing the difference between group means, how are between group and within group variability related to each other? Provide an example to support your answer. (2 marks)

QUESTION 2

a. If a two-factor ANOVA results in a significant main effect for factor A and a significant AxB interaction, explain why you should be cautious in interpreting the effect of factor A. (1 mark)

b. For the following research situations what would be your main effects and interaction effect. If there was a significant interaction effect what would that mean? (please be as clear as possible in your explanation):

A researcher hypothesizes that the effect of alcohol consumption on one’s motor skills depends on the person’s weight (underweight, normal, overweight), but that this may differ for men versus women. (2 marks)
A teacher is interested in seeing how attending class and reading the assigned chapters is related to her students’ performance on tests. She assesses each student in terms of how often they attend class (rarely, sometimes, regularly) and how often they read the assigned chapters (rarely, sometimes, regularly). (2 marks)

QUESTION 3

Ethel is interested in two methods of note-taking strategies and the effect of these strategies on the overall GPAs of college freshmen. She believes that men would benefit most from Method 1, while women would benefit most from Method 2. After obtaining 30 men and 30 women volunteers in freshmen orientation, she randomly assigns 10 men and 10 women to Method 1, 10 men and 10 women to Method 2, and 10 men and 10 women to a control condition. During the first month of the spring semester individuals in the two note-taking method groups receive daily instruction on the particular note-taking method to which they were assigned. The control group receives no note-taking instruction. Fall and spring GPAs for all participants are recorded and a score that is the difference between the spring and fall semester GPAs is calculated.

Below are the results from running a two-way ANOVA. Please answer the following:

What is the dependent variable? (0.5 marks)
What are the independent variables (factors)? (0.5 marks)
What is the research question(s) being addressed? (1 mark)
What does the descriptive statistics (graphical) tell us about the effects under study?

(1 mark)
What assumptions are being tested in the R output? Are these assumptions met? Please

provide statistical evidence. (2 marks)
What effects are being tested in the R output? (1 mark)
What does output from the ANOVA table tell us? (1 mark)
What type of follow-up analyses was conducted and why? Please interpret. (2 marks)

: Men
: Method1

      median
coef.var

0.300

0.469

: Women
: Method1

      median
coef.var

0.150

0.496

: Men
: Method2

      median
coef.var

0.275

0.027

: Women
: Method2

      median
coef.var

0.600

0.629

: Men
: Control

      median
coef.var

0.175

mean 0.335

mean 0.170

mean 0.305

mean 0.640

mean 0.165

mean 0.105

skew.2SE
   0.408

SE.mean CI.mean.0.95

var 0.052

var 0.033

var 0.037

var 0.032

var 0.022

var 0.021

normtest.W
     0.936

std.dev
  0.229

0.682
    skewness

1.076
    skewness

0.630
    skewness

0.072

SE.mean CI.mean.0.95

normtest.p 0.830 -----------------------------------------------------------------------------

skew.2SE
   0.342

kurtosis
  -0.645

kurt.2SE
  -0.242

normtest.W
     0.964

0.058

SE.mean CI.mean.0.95

std.dev
  0.183

normtest.p 0.096 -----------------------------------------------------------------------------

skew.2SE
   0.361

kurtosis
  -1.363

kurt.2SE
  -0.511

normtest.W
     0.869

0.061

SE.mean CI.mean.0.95

std.dev
  0.192

normtest.p 0.857 -----------------------------------------------------------------------------

0.278
    skewness

0.904
    skewness

skew.2SE
  -0.124

kurtosis
  -1.096

kurt.2SE
  -0.411

normtest.W
     0.979

-0.171

: Women
: Control

      median
coef.var

0.100

1.392
    skewness

0.560

0.046

kurtosis
  -0.759

0.105

kurt.2SE
  -0.284

   std.dev
     0.146

normtest.p
     0.512

skew.2SE
   0.019

kurtosis
  -1.443

kurt.2SE
  -0.541

normtest.W
     0.967

skew.2SE
   0.458

kurtosis
  -0.770

kurt.2SE
  -0.289

normtest.W
     0.906

0.056

SE.mean CI.mean.0.95

std.dev
  0.178

normtest.p 0.254 -----------------------------------------------------------------------------

                                                                      std.dev
                                                                        0.149

normtest.p 0.958 -----------------------------------------------------------------------------

0.047

SE.mean CI.mean.0.95

0.164

0.131

0.137

0.127

0.107

> leveneTest(gpa$gpaimpr~gpa$gender, data=gpa,center=mean)

Levene's Test for Homogeneity of Variance (center = mean) Df F value Pr(>F)

group 1 7.09 0.01* 58

---
Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 > leveneTest(gpa$gpaimpr~method, data=gpa,center=mean) Levene's Test for Homogeneity of Variance (center = mean)

      Df F value Pr(>F)
group  2    1.94   0.15

> #running Levene's test for assumption of HOV (INTERACTION EFFECT)
> leveneTest(gpa$gpaimpr, interaction(gpa$gender,gpa$method),center=mean) Levene's Test for Homogeneity of Variance (center = mean)

      Df F value Pr(>F)
group  5    0.57   0.72

Df Sum Sq Mean Sq F value Pr(>F) gender 1 0.020 0.020 0.61 0.43753

method 2 1.174 0.587 17.81 1.1e-06 *** gender:method 2 0.695 0.348 10.54 0.00014 *** Residuals 54 1.780 0.033
---

Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1

gender        0.0055
method        0.3200
gender:method 0.1894

0.011
0.397
0.281

eta.sq eta.sq.part

#selecting only Method1, run ANOVA, then follow-up tests

  Tukey multiple comparisons of means
    95% family-wise confidence level

Fit: aov(formula = gpaimpr ~ gender, data = gpaMethod1)
$`gender`
Women-Men -0.165 -0.3594851  0.02948506    0.0915581

diff        lwr        upr     p adj

#selecting only Method2, run ANOVA, then follow-up tests

  Tukey multiple comparisons of means
    95% family-wise confidence level

Fit: aov(formula = gpaimpr ~ gender, data = gpaMethod2)
$`gender`
Women-Men 0.335 0.161153 0.508847   0.000754

diff      lwr      upr    p adj

aquamarineox434

2. (12 marks) In a study of 85 individuals, food questionnaires were used to measure the change in polyunsaturated fatty acids (PUFA) intake from the beginning to the end of the study. In addition researchers measured a genetic marker in the TNF-αgene; for this analysis, we will take the two values of this TNF-αvariable to be A- or A+. The researchers also collected information on gender, age and BMI. The primary question of interest is whether TNF-αmodiﬁes the eﬀect of PUFA on HDL.

(a) (1 mark) Let TNFa be a variable with value 1 for A+ and 0 for A- TNF-αstatus and

let gender be 1 for males and 0 for females. State a linear model for mean change in HDL that includes the predictors PUFA, TNFa, PUFA×TNFa interaction, and eﬀects for gender, age and BMI.

(b) (1 mark) A summary of the ﬁtted model is:

Estimate Std. Error t value Pr(>|t|)

(Intercept) 0.037531 0.196980 0.191 0.8494

pufa 0.019143 0.009245 2.071 0.0417

TNFa 0.074433 0.034128 2.181 0.0322

gender -0.008988 0.031793 -0.283 0.7781

age -0.003895 0.002156 -1.806 0.0747

bmi 0.006777 0.004332 1.565 0.1217

pufa:TNFa -0.024575 0.017844 -1.377 0.1724

Write a short sentence to describe why we would even consider removing gender from the model (i.e., why we would not just be happy with the above model from

the outset).

(c) (2 marks) Below is a summary of the model ﬁt without gender. Using our 10% rule-of-thumb, is there any evidence that gender confounds the PUFA×TNFa eﬀect?

If so why, if not why not?

Estimate Std. Error t value Pr(>|t|)

(Intercept) 0.024467 0.190364 0.129 0.8981

pufa 0.018841 0.009130 2.064 0.0423

TNFa 0.074850 0.033897 2.208 0.0301

age -0.003783 0.002107 -1.795 0.0765

bmi 0.006835 0.004301 1.589 0.1161

pufa:TNFa -0.024496 0.017737 -1.381 0.1712

(d) (2 marks) The researchers decided to use the model with PUFA, TNFa, PUFA×TNFa, age and BMI for inference of PUFA×TNFa interaction. What are the degrees of

freedom for the t-distribution whose critical value we need to construct conﬁdence intervals for the interaction? What upper tail probability should you use for a 95%

conﬁdence interval?

(e) (1 mark) The appropriate critical value is 1.96. Construct a 95% conﬁdence interval for the interaction.

(f) (2 marks) State the null hypothesis and a two-sided alternative hypothesis for testing whether TNFa modiﬁes the eﬀect of PUFA on HDL.

(g) (1 mark) From the computer output, what is the p-value for this test?

(h) (2 marks) For ﬁxed age and BMI, what is the estimated eﬀect of a one-unit change in PUFA for a subject who is A- at TNF-α? For ﬁxed age and BMI, what is the estimated eﬀect of a one-unit change in PUFA for a subject who is A+ at TNF-α.

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ACMS10145 Lecture 10: Chapter 10

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