MICR 470 Lecture Notes - Lecture 2: Dirty Little Secret, Thymus, Aluminium Hydroxide
Document Summary
I assume he has influenced and changed the view of the human immune system. T cell: a lymphocyte of a type produced or processed by the thymus gland and actively participating in the immune response. They help fight infection by ingesting microorganisms and releasing. They help fight infection by ingesting microorganisms and releasing enzymes that kill the microorganisms. Tlrs: play a critical role in the early innate immune response to invading pathogens by sensing microorganism and are involved in sensing endogenous danger signals. Janeway had a very personal connection to immunology with both his father and his own experience with measles. This could have inspired him and drove him to be the great scientist that he was. The conclusion for the experiment in the early 1990"s was that co-stimulation was provided by a "non-specific" molecule carried by all b cells. The "dirty little secret" is that a foreign antigen alone was insufficient to elicit the adaptive immune response.
