BMCB 658 Lecture Notes - Lecture 19: Galactose, Prednisone, Bile Acid

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Structure: glycerol backbone, two oh esterified to fatty acids, one of esterified to phosphoric acid. Found almost exclusively in membranes: 40%-50% phosphoacylglycerols, 50%-60% proteins. Most abundant phosphoacylglycerols are derived from phosphatidic acid: glycerol is esterified with two molecules of fatty acid and one of phosphoric acid. Most abundant fatty acids in phosphatidic acids: r1 usually palmitic acid (16:0) or stearic acid (18:0, r2 often unsaturated fatty acid. Long-chain fatty acid esterified to a long-chain alcohol. Protective functions: animals: coat fur, feathers, skin, plants: coat leaves, stems, fruit. Beeswax serves structural function: triacontanoyl palmitate, honeycomb is firm at 25 c (impervious to water) Principal component of spermaceti, wax produced by whales. Principal component of carnauba wax from brazilian wax palm. Ceramides: one fatty acid linked to the amino group of sphingosine by an amide bond. Glycolipid: a compound in which a carbohydrate is bound to oh of the lipid. Common in membranes of brain and nerve cells.

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