BIOL 1115 Lecture 10: Chapter 10

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Multicellular organisms: main benefit of being multicellular, division of labor, have larger genomes = larger proteomes, additional proteins used for, cell communication, arrangement and attachment of cells, cell specialization. Proteins of ecm: grouped into 2 categories, adhesive, connects cell to the ecm. Ecm: polysaccharides, polymers of glucose, most abundant, glycosaminoglycan (gags) Functions: resist compression, two gag examples (vertebraes, chondroitin sulfate, cartilage, hyaluronic acid, chitin. Found in skin, eyes, joint fluid: another ecm component, nitrogen containing polysaccharide. Forms outside the plasma membrane: protective, main component, cellulose. Cell junctions: to become multicellular, cells must be linked together, accomplished via cell junctions. 3 types in animal cells: 2 types in plant cells. Anchoring junctions (animal cells: attach cells to each other and to the ecm, mechanically strong, rely on cell adhesion molecules (cams, cadherin and integrin. Forms tight seal between adjacent cells: prevents ecm from leaking between cells.

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