BIOL 1117 Lecture Notes - Lecture 11: Dermis, Dendritic Cell, Keratinocyte
Document Summary
Largest and heaviest organ thick skin has no oil glands or hair. Below at the hypodermis is a lot of fat. Keratin: well packed: desmosomes support tight junctions. Skin is first step in making vitamin d. Sensitive to vibrations through sensation receptors on skin transmit signals to brain. Constrict or dilate depending on temperature: dilation: increase heat loss, constrict: decrease. Dead cells on top are highly keratinized. Adult stem cells on base layer, undifferentiated: can become keratinocytes. Melanocytes: melanin is a pigment/type of protein that is effective at absorbing uv radiation: as they engulf they accumulate the melanin. Dendritic cells: guard cells, first line of protection. Know top zone papillary layer contains areolar tissue.