BIOL 1121 Lecture 35: 13. Respiratory Cycle 3

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Karina da rosa: respiratory system (con"t, factors that affect o 2 unloading i. ii. iii. Haldane effect: low levels of deoxyhemoglobin (hbo 2 ) enables blood to transport more carbon dioxide, hbo 2 binds co 2 better than hbco 2, neutral control of breathing i. ii. iii. Skeletal muscles of ventilation cannot contract without nerve stimulation. Lungs do not have autorhythmic pacemaker (pacemaker is in the brain) Involuntary and unconscious: medulla oblongata and pons, respiratory control centers i. Vrg : ventral respiratory group: location of the pacemaker, generates the primary rhythm of breathing, nucleus in the medulla, rhythm-generating b. Integrating center: receives input from higher brain centers, respiratory center in pons and internal sense receptors, transmits output to the inspiratory spinal motor neurons and to the vrg neurons iii. Prg : pontine respiratory group: modifies the rhythm of the vrg (inspiration to expiration, receives input from the higher brain centers, transmits output to the drg, sensory communication to drg i.

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