PSYC 1101 Lecture 1: Exam 2 Study Guide Fall 15
31 May 2016
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Tolerance: with repeated exposure, the drug"s effect lessens; bigger doses are needed to get the same effect. Withdrawal: absence of drug causes physical pain. Be familiar with the criteria necessary to make such a diagnosis. Name the brain areas that are part of this pathway. Dopamine reward pathway: activates with the gaining of anything good (food, sex, etc. ) Continued drug use sharply reduces the number of dopamine receptors in the brain"s reward system. Down-regulation: brain adjusts by cutting off number of receptors dopamine can bind to. Agonists: increases the effects of neurotransmitter activity (ex. activates post- synaptic receptors, etc. ) Antagonists: decreases the effects of neurotransmitter activity (ex. They block the transporter that recycles serotonin from the synaptic cleft, thus increasing levels of the mood-regulating neurotransmitter in the brain. Serotonin agonists: be able to link specific drugs to their larger drug class (e. g. , morphine is an opiate which is considered a depressant; cocaine is a stimulant, etc. )
