PSYC 3406 Lecture Notes - Lecture 7: Monoamine Oxidase Inhibitor, Electroconvulsive Therapy, Monoamine Oxidase

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Long-term not as effective as short-term: behavioral therapy. 50 to 60% found elimination of symptoms. Sociocultural approaches: multicultural treatments, family-social treatments. Electroconvulsive therapy (ect: effective for severe depression. 60 to 80% find improvement: 100,000 us residents undergo ect annually, 6 to 12 treatments, three times per week, relieves suicidal thinking, not really sure why it works. Inhibits action of monoamine oxidase, preventing the enzyme from breaking down neurotransmitters (particularly norepinephrine) Increase norepinephrine and serotonin by interfering with reuptake. Interfere with reuptake, but with more specific effects. Tcas: stomach upset and other problems, such as constipation, dry mouth, blurred vision, and drowsiness, lowered blood pressure, weight gain, tremors and sweating. Inability to urinate (urinary retention): loss of sexual desire or ability, confusion or delirium in older adults, cardiac problems in those with heart disease, fatal if overdose. Maois: daytime sleepiness, dizziness or lightheadedness, low blood pressure, diarrhea, dry mouth, altered sense of taste, nervousness, muscle aches.

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