CHEM 3650 Lecture Notes - Lecture 10: Lipid Bilayer, Cell Membrane, Glycerophospholipid

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8 Jun 2017
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Phospholipids; polar head with two fatty acid tails (hydrophobic) Peripheral protein attached on only one end of the membrane; can be either external or internal. Three main classes of lipids cholesterol, phospholipids, glycolipids. Cholesterol backbone of steroids ex. testosterone, estrogen, etc. Structure of glycerophosopholipids backbone is glycerol two fatty acid chains phosphate with an alcohol on the third chain. Structure of sphingolipids (phospholipid) sphingolipid backbone one fatty acid chain phosphate with choline chain. Structure of sphingolipids (glycolipids) sphingolipid backbone one fatty acid chain mono or oligo- saccharide. Gangliosides subset of glycosphingolipids that contain sialic acid (nana) Globoside generic name for a glycosphingolipid with more than 3 saccharide units that does not have a specific name. Glycerophospholid (phosphatidyl choline) fatty acid; saturated so more solid at room temperature more compact structure; unsaturated and distance gives fluidity. Sphingomyelin prominent in myelin sheath; problems arise with movement issues, numbness and tingling.