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Class Notes for BIOL-UA 21 at New York University (NYU)

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NYUBIOL-UA 21Mark SiegalFall

Class notes - Lectures 1-9.docx

OC12618063 Page
14 Oct 2013
41
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 19: Condensin, Conformational Change, Tamoxifen

OC8501995 Page
22 Dec 2016
2
Lecture 19: transcription regulation ii: how transcription factors are regulated: Modular structures: distinct protein domains have distinct structures
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 24: Contig, Tata Box, Human Genetic Variation

OC8501996 Page
22 Dec 2016
0
Lecture 24: sequencing: genomics: study of the structure, function and evolution of genomes, chemical sequencing, sanger sequencing, human genome proje
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 23: Ubiquitin, Lysine, Transposable Element

OC8501995 Page
22 Dec 2016
0
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 27: Biome, Rna Interference, Crispr

OC8501995 Page
22 Dec 2016
2
Lecture 27: systems biology: system: interactions between components. Protein-metabolite: transcription factor binding to regulatory region. Post trans
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 21: Sanger Sequencing, Dosage Compensation, Down Syndrome

OC8501997 Page
22 Dec 2016
1
Lecture 21: genome editing: genome editing: is done by programmable nucleases that enable targeted modi cations in cultured cells, as well as whole ani
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 18: Electrophoretic Mobility Shift Assay, Myod, Deoxyribonuclease I

OC8501993 Page
23 Nov 2016
1
Lecture 18: regulation of transcription i: one genome encodes for many types of cells: Different types of cells express different genes, making speci c
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NYUBIOL-UA 21SiegalSpring

BIOL-UA 21 Lecture 3: Genomes and Diversity Lecture 3

OC9592832 Page
29 Nov 2017
0
1866- gregor mendel, austrian monk, discovered the laws of inheritance. 3" 5" 3" ribosome reads dna and makes protein out of it; scans along 5" end for
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 3: Rna Polymerase Iii, Rna Polymerase Ii, Rna Polymerase I

OC8501995 Page
1 Oct 2016
21
Lecture 3: central dogma ii: every cell in your body has identical dna. In these cells, different genes are activated differently. A decision is made e
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture 22: Lecture 22

OC8501995 Page
22 Dec 2016
1
Lecture 22: post-transcriptional control: when the germ line is rst formed, transcription of all genes is repressed. All regulation is post- transcript
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NYUBIOL-UA 21Mark SiegalFall

BIOL-UA 21 Lecture Notes - Lecture 26: Mutation, Exon, Chromosome

OC8501995 Page
22 Dec 2016
2
Centrifugation of column based separation based on a property: size, charge, shape of protein etc. First, separate the proteins on gel by change ( rst
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NYUBIOL-UA 21Mark SiegalSpring

BIOL-UA 21 Lecture Notes - Lecture 24: Sanger Sequencing, Bacs, Reference Genome

OC8501546 Page
18 Mar 2016
4
Putting bacs in order with re mapping. Define a set of bac clones that spans genome with minimal redundancy. Minimal tiling path = with 5 bacs you can
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