NEURL-UA 100 Lecture Notes - Lecture 9: Second Messenger System, Cribriform Plate, Brainstem

• School: New York University
• Department: Neural Science
• Course: NEURL-UA 100
• Professor: Tony Movshon

Document Summary

Lecture 9: 10/11/17: sensory receptors are specialized to transduce a particular type of stimulus energy into electrical signals, chemoreceptor, photoreceptor, me(cid:272)ha(cid:374)o(cid:396)e(cid:272)epto(cid:396): (cid:272)ha(cid:374)(cid:374)els i(cid:374) (cid:373)e(cid:373)(cid:271)(cid:396)a(cid:374)e that"s se(cid:374)siti(cid:448)e to ph(cid:455)si(cid:272)al st(cid:396)et(cid:272)hi(cid:374)g of (cid:373)e(cid:373)(cid:271)(cid:396)a(cid:374)e gates open. If you engineer sporadaline receptors in sweet cells animals now favor that taste-containing fluid. If receptor activated in bitter cells, animals will avoid the taste-containing fluid since it will activate the bitter cells. There is a hard-coded notion of signals from particular receptors mean to the mouse if mouse thinks the receptor is encoding bitter taste even though the actual taste is hijacked by receptor manipulation to be a non-taste. In another possible model, each taste receptor cell expresses many diff taste receptor proteins, so each cell responds to many diff tastants and signals are all mixed in the nerves and somehow get pulled apart and decoded later.