EEOB 2520 Lecture Notes - Lecture 6: Electrochemical Gradient, Electric Charge, Channel Aka
9 Sep 2018
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Potential that makes all the others possible. Electrical charge separation across pm due to distribution of charged. Aka sodium ions want to come inside the cell bc the inside of cell is negative (it moves in the same direction as the concentration gradient) For potassium, they also want to come inside when talking electrochemical gradient, but it"s conc gradient wants it to go out (one part of gradient saying come in; other part saying go out) When going in opposite directions, figure out which one dominates--which is the bigger vector; do vector addition/subtraction (one has to dominate) -we don"t have to figure out whether an electrical gradient or chemical gradient is bigger (beyond the scope of this class) Measurement of voltage gradient - the difference in voltage between outside and inside of cell. Vm = voltage gradient across the membrane (m=membrane) Most cells at rest: vm = -70 mv (millivolts)
