EEOB 2520 Lecture Notes - Lecture 15: Insulin-Like Growth Factor 1, Homeostasis, Bone Density

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Not released consistently; can even have a circadian rhythm to it. Not always being released bc we don"t always want to continually grow; most growth happens during developmental stages. Stimulates igf-1 (in liver and bones); increase mitosis. Our bones need to grow in order to get us taller. Igf-1 sets us up to be able to to mitosis so we need them to help us with epiphyseal plates for bone growth. We need two places where we can release igf because the bones themselves have a need for them. Just relying on liver does not give us as much and as quick of a bone growth as if the bones are able to make igf themselves. Liver gets us igf for the whole body; bone gets us igf for itself too grow longer) Growth hormones also directly get end responses (specifically to skeletal muscle to increase development); stimulates muscle development.