EEOB 2520 Lecture Notes - Lecture 34: Calcitriol, Heart Failure, Parathyroid Gland

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Amount of blood that leaves the heart per contraction. Equation sv = edv - esv: edv end diastolic how much blood is in the heart right before contraction, esv end systolic how much blood is in the heart after contraction. Ways to regulate: increase edv increase sv. Increase a little bit = stretch the heart a little = potential for cross bridge cycling increases (can contract better) increase sv (send more heart out) If we increase edv too much = congested heart failure = can"t contract the heart: arterial pressure decrease sv. The resistance the heart has to pass to send blood out makes it harder. More blood in heart after contraction because harder to pass pressure and get out: sympathetic increase sv. Epi and ne going to heart = increase ability to contract = will eject more blood from heart. Does not need an increase in edv.

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