PSYCH 5681 Lecture Notes - Lecture 9: Basolateral Amygdala, Dendritic Spine, 5-Ht Receptor
Document Summary
Allostasis, biological sensitivity to context, teratogen exposure, head injury. The human stress response system is variegated and complex; it is usually defined by functional reactivity of the sympathetic-adrenomedullary (sam) arm and the limbic- hypothalamic-pituitary-adrenal (lhpa) axis (see doom & gunnar, 2013; jacoby et al. , Exposure to real or perceived threat/stress triggers a cascade of reactive and interactive processes across multiple biological systems: the hypothalamus initiates a sympathetic nervous system (sns) response through the sympathetic-adrenomedullary (sam) arm, which: Stimulates the adrenal medulla to produce catecholamines, including epinephrine and norepinephrine (i. e. , adrenaline and noradrenaline) Activates, through adrenaline release, peripheral organs, including the heart and sweat glands, which facilitates fight/flight/freeze (f/f/f) responding. Shifts blood from digestive to skeletal muscles. Sns activation serves a mobilizing function, which is very rapid, and shifts metabolic resources from vegetative functions to immediate coping needs: the hypothalamus also excretes corticotropin releasing hormone, which: Triggers subsequent release of adrenocorticotropin from the pituitary gland, which in turn .