BIOS 3430 Lecture Notes - Lecture 11: Dihydropyridine, Semipermeable Membrane, Ryanodine

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Essential terminology: myofibril, sarcomere, myofilament, actin, myosin, troponin, tropomyosin, cross-bridge, z-disk, a band, i band, h zone, m line, rigor mortis, sliding filament theory, triad, t tubule, sarcoplasmic reticulum, dhpr, ryr. Blocks inhibitory neuron: tetanus: define the following: myofilaments, myofibrils, muscle fibers, and muscles. Actin: polymerization of g-actin (two-stranded helix of f-actin); tropomyosin + Including actin and myosin troponin complex (controlling muscle contraction) Myofibrils: elongated contractile threads found in striated muscle cells. This is the rigor conformation (rigor moris, when muscles become stiff after death because of the absence of atp. Actin and myosin heads are rigidly fixed in place until a new molecule of atp binds to the myosin head and triggers unbinding from actin): globular myosin head readily binds atp and detaches from myosin. The detachment requires the binding of atp to change the conformation of myosin s actin-binding site, but it does not require the energy derived from atp.