BIOS 4500 Lecture Notes - Lecture 26: Lean Body Mass, Body Fat Percentage, Subcutaneous Tissue

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Cortisol is the only counter regulatory hormone that breaksdown protein and mobilizes it. When the ratio is >4-> proteolysis occurs (protein breakdown) The morning after an overnight fast the ratio is already high-> proteolysis. W/ glucose infusions or after consuming food there is a decreased ratio b/c glucose stimultes insulin secretion-> no proteolysis. Fa availability from diff. lipid stores for oxidation during moderate-intensity exercise: Mostly occurs in upper-body subcutaneous adipose tissue, but also lower-body subcutaneous, intra- abdominal (visceral) adipose tissue, intramuscular triglycerides, plasma triglycerides, and other. >differ b/w tissues due to the diff. receptors found at each. ->those w/ more re(cid:272)eptors have higher rates of lipolysis-> more oxidation-> more ffa. Metabolic patterns in the injured, burned, or surgery patients. Metabolic pattern does not undergo the same adaptation as the normal fasting patients. The normal regulatory mechanisms are overwhelmed by increases in the counterregulatory hormones.