BIOS 4500 Lecture Notes - Lecture 24: Bone Age, Precocious Puberty, World Health Organization

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Growth- (cid:862)the organized addition of new tissue as occurs normally in development from infancy to adulthood. This process is complex and depends on the interplay of genetic, nutritional, and environmental influences as well as actions of the endocrine system. (cid:863) *basic medical. Growth hormone can influence adult stature in man only about 30% of genetic potentially. If destined by genetic makeup to be 6 feet tall, will attain a height of about 4 feet in the absence of gh. >it is unlikely that height will exceed 8 feet w/ massive doses of gf. Gf is a facilitator of expression of genetic potential for growth, rather than the primary determinant. Yet to understand what determines genetic potential for growth *basic medical endocrinology pg. 100% of growth is expected as an adult. Lymphoid tissue peaks at childhood and then regresses during adulthood. At puberty, there are major changes in certain genital tissues.

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