PYSO 001 Lecture Notes - Lecture 5: Portal Vein, Hepatic Portal System, Bile Canaliculus

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Hepatic portal system circluation of blood between intestine and liver absorbed products of digestion enter liver before entering general circulation by way of the hepatic portal system (capillaries in digestive tract vein capillaries in liver vein) Liver clears the blood of variety of compounds by removing them from blood and excreting them into the intestine with bile. At each corner hepatic portal vein, hepatic artery, and bile duct. Hepatic sinusoids capillaries that carry blood to central vein. Bile canaliculi carries bile to bile duct, which drains into hepatic duct, which carries bile away from liver. Enterohepatic circulation: compounds that recirculate between small intestine and liver (e. g. bile salts recirculate about 6-10 times per day) Functions: bile production and secretion, bile: yellowish green fluid containing bile salts, bilirubin, cholesterol, inorganic ions and a variety of exogenous compounds (drugs, bilirubin heme from rbcs is converted to bilirubin; produced by spleen, liver and bone marrow.

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