MICRB 201 Lecture Notes - Lecture 6: Ribosomal Rna, Cell Membrane, Lysosome

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13 Sep 2017
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Eukaryotic cells are characterized by the presence of membrane-enclosed organelles (fig a. Compartment within cell where distinct metabolic reactions occur. Harbors oranelles and filamentous components of the cytoskeleton (fig 25. 30a) (slide 2) Endoplasmic reticulum: role in metabolism and transport of proteins and lipids (er; fig. 2. 1,14) (slide 3 and 4: network of tubules and flat sacs involved in protein and lipid transport, two forms: Rough er: outer surface studded with ribosomes. Involved in vesicular transport and modification of proteins. Involved in lipid metabolism and detoxification of chemicals e. g. pesticides and carinogens. Golgi apparatus: role in sorting and packing of macromolecules (fig. A2. 14) (slide 4: stack of flattened sacs closely assoiciatied with er, receives material from the er directs lipids and protein to their final destination e. g. secretory vesicles, plasma membrane, lysosomes, etc. Lysosomes: low ph environment and role of hydrolytic enzymes (fig a2. 13) (slide 5: required for intracellular digestion of: Macromolecules (old or non-functional proteins, nucleic acids, carbohydrates, etc)

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