NURS 225 Lecture Notes - Lecture 15: T Helper Cell, Regulatory T Cell, Allergic Rhinitis
Document Summary
Cd4- helper t cells: become activated when their tcr interacts with antigens on a. Primary (congenital): not usually inherited, sex linked traits. May be minor, and short, or life threatening. Type 1: ige mediated: most common, develops upon exposure to an antigen. Shows a (cid:1688)classic(cid:1689) allergic response: can be environmental, medical, pharmalogical. (ex. Have high total serum and allergy specific ige levels and increased eosinophils, mast cells, and basophils. Allergic rhinitis and food allergies are common examples. (note: fever is absent: anaphylaxis. Depends on severity of reaction not quantity. Graves" disease: antibody mediated, the tissues expressing the ag form the clinical manifestations. Igg or igm binds to tissue specific ag. Type 3: immune complex: antigen antibody immune complexes in bloodstream, which is deposited later in the epithelium causing a massive immune response. Can cause cell death and tissue injury. Cd4 helper t cells activate monocytes and macrophages by the release of large amounts of if.
