BIOSC 1250 Lecture Notes - Lecture 10: Red Blood Cell, Extracellular Fluid, Hematocrit

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23 Nov 2017
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Goal of cardiovascular system: maintain adequate delivery of oxygen, nutrients, and removal of wastes from all tissues in the body: also to monitor tissue integrity (cid:894)(cid:449)o(cid:374)"t talk (cid:373)u(cid:272)h a(cid:271)out(cid:895) & is avenue for signaling. Cardiovascular system = heart, blood vessels, & blood: aka circulatory system. Amount of blood in circulatory system: total blood volume = ~5. 5 l (70 ml of blood per kg, hemoglobin = ~15g/dl (decaliter = 10 l) Separation of blood by centrifugation: hemoglobin: main protein in red blood cells, red cell count = ~5 million, hematocrit = ~45, hematocrit = red blood cells, white cell count = several thousand. Plasma: mostly water, has ions like interstitial fluid, gasses, nutrients, wastes, hormones & messenger molecules, proteins are 7% or 7g/100ml. White blood cells = 1: albumin, globulins, fibrinogen. Plasma vs serum: plas(cid:373)a has fi(cid:271)ri(cid:374)oge(cid:374) & other (cid:272)lotti(cid:374)g fa(cid:272)tors (cid:894)(cid:271)lood has(cid:374)"t (cid:271)ee(cid:374) allo(cid:449)ed to (cid:272)lot, serum lacks clotting factors & has been allowed to clot.

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