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Lecture 32

NROSCI 0081 Lecture 32: Herbal Supplements, Herbal Drugs, and Environmental Toxins

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April Dukes

Lecture 32 4717 Herbal Supplements, Herbal Drugs, and Environmental Toxins Reminder: A drug is any chemical, not essential for life, that has a biological effect on the body A psychoactive drug is any drug defined as above that has an effect on neurological function and behavior Some herbal supplements contain psychoactive drugs Natural drugs o Drugs derived from a natural source Could be any form (powder, capsule, liquid) o Many illicit drugs can be thought of as herbal Many natural drugs are sold as dietary supplements Medicinals and risks o It is important to know that ALL medicines, both prescription and OTC, have risks as well as benefits Risks of medicines are the chances that something unwanted or unexpected could occur (side effects) Risks range from the less serious (upset stomach) to very serious (liver damage, death) o Herbal remedies do not have to follow the same strict rules that prescription drugs do Manufacturers do not have to prove that the product is sage, effective, r that it contains the ingredients on the label This is allowed under their classification as dietary supplements 1906 Pure Food and Drug Act o The truth in advertising law o Producers had to disclose on their labels what was in their products 1938 Food, Drug, and Cosmetic Act o Gave authority to oversee the safety of food, drugs, and cosmetics to the U.S. Food and Drug Administration Dietary Supplement Health and Education Act (DSHEA) o Defined by US Congress in 1994 o Any product taken by mouth that contains a dietary ingredient intended to supplement the diet Includes nutrients and nonnutrients derived from foods Vitamins, minerals, herbal or botanical extracts, enzymes, metabolites o DHSEA regulates dietary supplements as foods, not drugs Requires labeling to indicate it is a dietary supplement Dietary supplements are not considered food additives Food additives require premarket toxicology testing and risk assessment by the U.S. FDA o Under DSHEA, it is the intended use of a product that distinguishes a drug from a dietary supplement Drug: Intended to diagnose, treat, prevent, or cure disease Dietary supplement: Not intended to diagnose, treat, prevent, or cure disease
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