BIO 102 Lecture Notes - Lecture 10: Signal Transduction, Cardiac Muscle, Endocrine System
16 Jan 2019
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Document Summary
Direct mvmnt through gap junctions linming cytoplasm of adjacent cells. Ions flowing between cardiac muscle cells synaptic neurotransmitters diffusion from neuron across acetylcholine synaptic cleft to cell bearing appropriate receptors paracrine. Local hormones diffusion through extracellular fluid to nearby cells bearing appropriate receptors prostaglandins endocrine hormones. Carried in bloodstream to distant cells bearing appropriate receptors insulin. Amino acid-derived hormones composed of 1 or 2 modified amino acids. These bind to receptors on the surface of/inside of a target cell. 3- hormone leaves capillaries and diffuses to all tissues through extracellular fluid. 4- hormone affects cells bearing receptors that hormones can bind to. 5- hormone cannot affect cells that bear receptors they cannot bind to. Actions of peptide and amino acid-derived hormones on target cells messenger. Hormone receptor complex binds to dna, which causes rna polymerase to bind to a promoter site for a specific gene. Hormone binds to receptor on plasma membrane of target cell.
