NUR 326 Lecture Notes - Lecture 6: Angiotensin Ii Receptor Blocker, Calcium Channel Blocker, Systolic Hypertension

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20 Mar 2017
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Components of the conduction system of the heart. Review of bp control: pressure in cv. Heart rate: baroreceptors aortic arch, carotid arteries (look at the pressure, medulla cardiovascular or vasomotor center. Renin-angiotensin (in the liver) aldosterone system. Control na and h2o: elimination/retention effect cardiac output and systemic bp. Cate(cid:272)hola(cid:373)i(cid:374)e"s (cid:894)(cid:374)orepi(cid:374)ephri(cid:374)e, released fro(cid:373) sy(cid:373)patheti(cid:272) (cid:374)er(cid:448)e ter(cid:373)i(cid:374)als(cid:895) Epinephrine released from adrenal medulla increase bp via vaso constriction. Angiotensin 2 goes to kidney and releases aldosterone. Alpha 1: found in blood vessels, in iris, in bladder (can cause vasoconstriction and increase peripheral resistance) Alpha 2: located on nerve membranes and act as modulators of norepinephrine release (too much stimulation flow back to nerve, hold off on norepinephrine release) also found on beta cell in pancreases helping to moderate insulin release. Beta 2: in smooth vessels in muscle in blood vessels, in bronchi, periphery and uterine muscles. Beta 3: in kidney help to stimulate the renin-angiotensin-aldosterone system.

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