01:119:115 Lecture Notes - Lecture 13: Drosophila Melanogaster, Y Chromosome, Eye Color

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:115
• Professor: Daniel Stern Cardinale

Document Summary

Thomas morgan: early 20th century, experimental embryologist. Morgan originally a skeptic of mendel"s work and chromosome theory: significance of morgan"s work. Chromosomal theory fit what was known about mendel"s. Morgan: 1st experimental support genes on chromosomes: drosophila melanogaster. 4 pairs of chromosomes - 3 pairs of autosomes, 1 pair of. Wild type: most common phenotype for a chracter in natural populations (c. 3. a. 1) ex. red eyes for fruit flies. Mutant phenotype: alternatives to wild type (c. 3. b. 1) ex. white eyes for fruit flies. In drosophila, gene gets symbol based on 1st observed mutant. Example: (c. 4. c. 1) allele for white eyes = w (c. 4. c. 2) allele for red eyes = w+ (c. 4. c. 2. a) + symbolizes wild type. F1= all offspring have red eyes (c. 5. b. 1) red eyes dominant. C. 5. c) red-eyed female f1 x red eyed male. Ratio of x chromosomes to sets of autosomes (a) determines sex. Unique inheritance patterns for genes on sex chromosomes. Sex chromosomes: autosomes: any chromosome other than a sex chromosome.