01:119:115 Lecture Notes - Lecture 14: Frederick Griffith, Erwin Chargaff, Nucleic Acid Double Helix
27 Sep 2016
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Dna (lecture 14: dna = genetic makeup, found within distinct units of heredity a. i. Consensus: proteins carrie genes because they"re made all the time and they"re all over the body a. ii. 1. a. 20 seems bigger so must be the wrong answer a. ii. 1. b. This was accepted until : frederick griffith (1928, bacteriologist and embryologist a. i. 1st to show evidence against/reject the protein hypothesis a. ii. 1. People still didn"t believe: subject: streptococcus pneumoniae b. i. b. ii. Bacteria with 2 strains pneumonia in humans b. ii. 1. b. ii. 2. lethal to mice. Smooth, shiny colony when grown on agar plate. Cause sickness b. ii. 2. b. b. ii. 2. b. i. b. ii. 2. b. ii. not smooth(rough) Immune system gets rid of it super quick b. ii. 2. b. ii. 1. a. i. Take smooth type inject into mice mouse dies. Rough inject into mice mice lives. Smooth add heat mouse lives b. iii. 3. a. because killed bacteria b. iii. 4. When proteins are heated they end up being b. iii. 4. b. ii. b. iii. 4. b. iii. denatured they no longer are alive/active.
