01:119:115 Lecture Notes - Lecture 1: Neuroplasticity, Signal Transduction, Cerebral Cortex

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Brain and ns: consists of circuits of neurons and supporting cells. A. 1. primary information transmitting cells - neurons: overall structure is established during embryonic development. B. 3. a) establish connection for life: basic layout set but not set in stone - neuronal plasticity. C. 2. modified after birth brain dynamic; constant and the basis to form memories connections between neurons can be modified. C. 2. a) (c. 2. a. 1) most changes occur at synapses between neurons (c. 2. a. 2) changes activity dependent (c. 2. a. 2. a) connections must be remembered: don"t use it lose it. D. 3. more connections 0 high activity; low activity - loss of activity multiple active synapses - stronger response at synapses real world example: autism. Memory at synapses: anatomical/physical event occurs at synapses in brain. A. 1. dependent on neuronal plasticity and activity: short term - up to 30 seconds, 4-7 items, information is released if it is not used -ram. Sent to ltm: long term - theoretically infinite, hard-drive.

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