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Lecture 1

01:119:115 Lecture 1: Lecture 1: Memory and Learning

2 pages85 viewsFall 2018

Department
Biological Science
Course Code
01:119:115
Professor
Stern-Cardinale
Lecture
1

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I. Memory and Learning
a. Neural development
Nervous System consists of neurons (primary functioning cells) and
supporting cells
Developmental Process involves gene expressions and signal
expression
b. Neuronal Plasticity
Neuronal Plasticity = The ability of the nervous system to be
modified after birth
Dynamic; can be remodeled at the synapses (junctions between
neurons)
Changes are activity dependent; they must be used often if not the
synapses will not be needed anymore and start to disappear
Memory: use it or lose it
High activity = many connections, low activity = lose connections
Synapses take a lot of energy to maintain so if you don’t use it you
lose it to save energy
Multiple active synapses = stronger response at all synapses
(easier to remember something if you connect it w/ something)
c. Memory
Memory = physiological event occuring at synapses dependent on
neuronal plasticity and activity
Short Term Memory (STM) = information is stored for a short time
(5-7 seconds) and released if it’s irrelevant
Long Term Memory (LTM) = information that needs to be retained,
when it is needed it is retrieved into STM
Memory DOES NOT = learning
Learning = use of knowledge/ experiences (memory) to decrease
the likelihood of a negative outcome
One does better as a result of learning
d. Long Term Potentiation (LTP)
Lasting increase in the strength of synaptic transmission -
physiological changes
Facilitates memory and retrieval
Activity dependent = robust synapses
Learner needs to use the information for long term potentiation
Use of information is a sorting process
Use → important → retained
Not used → unimportant → discarded
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