01:119:115 Lecture Notes - Lecture 10: Nucleosome, Cell Division, Chromatin

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October 2, 2014: introduction, cell theory, some cells are described as terminally differentiated (specialized) Do not divide: single-celled organism, multi-cellular organism. New organism results when cell division occurs: allows organism to grow and develop, renewal & repair (cell division continues after cell fully grows) Dna: dna double helix wrapped around proteins (done in a high organized, histones- proteins found in eukaryotic cells; associate with, nucleosome- contains 8 histones, 146 nucleotide pairs of dna histones + dna = nucleosomes. Linker dna consists of 60 of the nucleotide pairs [fig. 16. 22: gene, basic unit of information structure of a protein, 100s-1000s of genes on a chromosome, each gene is found at a particular locus on a chromosome. Locus is the location on a chromosome where gene is found: chromatin- dna/protein material when it is in its dispersed state, genes are arranged in linear sequence, humans have about 20,000 genes. Most of the time during the cell cycle the dna is in the.

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