01:119:115 Lecture Notes - Lecture 13: Thomas Hunt Morgan, Heterogametic Sex, Color Blindness

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~ 1902: scientists began to develop the chromosome theory of inheritance : genes have specific loci on chromosomes, chromosomes undergo segregation and independent assortment. Let"s review in figure 15. 2 the chromosomal basis of mendel"s laws (figure 15. 2 a & b: morgan and the chromosome theory of inheritance. 1. evidence that xs are the location of mendel"s heritable factors : morgan"s choice of experimental organism. Morgan chose to study drosophila melanogaster, a common species of fruit fly. A convenient organism for genetic studies: the produce 100"s offspring, a generation every two weeks. Traits studied in drosophila melanogaster: wild type. Phenotype for character most commonly observed in population. Example: white eyes (first mutant found in male: for a given character, gene given symbol for 1st mutant example: allele for. Red eyes = w+ (figure 15. 3: correlating behavior of a gene"s alleles with behavior of a chromosome pair. Morgan"s experiment: he mated red-eyed female x white-eyes male (insert figure 15. 4)

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