14:125:201 Lecture Notes - Lecture 6: Carbohydrate, Aspirin, Methylene Blue

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Monocytes: wbcs which phagocytose pathogens to be presented to natural killer. Lymphocytes: primary immune system wbc; multiple types including natural killer cells (destroy viruses / bacteria) and b-cells (long term immunity). Red blood cells: concentration: 5 million cells / l. Use hemoglobin to carry oxygen around body; unable to reproduce via mitosis. White blood cells: concentration: 5000-10,000 cells / l. Platelets / thrombocytes: concentration: 300,000 cells / l. Clot blood; signal coagulation proteins to target the clotted areas. Plasma / serum: 50-60% of blood volume; coagulants, proteins, lipids, etc. dissolved in solution. Somatostatin gene: first replicated in e. coli; codes for production of human growth hormone. Length of time for a biotechnology product to move through all testing and trial phases: 10-15 years. Pulmozyne: enzyme that treats cystic fibrosis; around 3000 children per year are born with cf. Genetically engineered human insulin: produced in e. coli; replaced common insulin produced in livestock.

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