01:146:328 Lecture Notes - Lecture 10: Brugia Malayi, Loa Loa, Loa Loa Filariasis
Document Summary
Eggs hatch in uterus and microfilaria released: advanced embryos, sheathed - retain flexible eggshell as covering membrane blood-dwelling unsheathed - tissue dwelling spp, wuchereria barcrofti, brugia malayi, onchocerca volvulus, loa loa. Wuchereria banecrofti suitable vector decreased body temperature, increased acidity, decreased excretion by h2o in kidneys. 17-1 overview life cycle lymphatic filariasis or elephantiasis mainly in lower half of body females - 8-10 cm males - 40 mm lubricant and anticoagulant. Elisa subcutaneous tissue hyperkeratosis - hypertrophy of outer skin layer fissures, nodules, warty appearance elephantiasis (lf) - repeated acute and severe attacks chronic lymph blockage fibrous tissue elephantoid limbs/organs fibrous tissue + fat psychological and social impact. Dec fortified salt: dec - single annual dose, albendazole - single annual dose donated by glaxosmithkline. sh cost: ivermectin - single annual dose donated by merck. sh cost common cooking salt to which dec has been added eliminate mf.