01:146:356 Lecture Notes - Lecture 20: Respiratory Acidosis, Metabolic Acidosis, Alkalosis

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Systems physiology notes: regulation of respiration (day 2) If the vagus is not activated, inspiration is long and slow = herring-brewer. The tidal volume is immense as well. This reflex = the negative response to stress on the system. Chemical control: designed to detect the po2 via peripheral chemoreceptors, Po2 is the primary stimulus of the peripheral. Carotid sinus = stretch receptors responding to changes in pressure. Chemoreceptors: respond to chemical changes, changes occurring outside the vessel. Axons pass through the same afferent nerves to communicate with the brain. On the ventral surface: a second set of axons exist, called the aortic bodies. Adults have very small ones (about 2 milligrams) Per 100 grams of tissue there is about a 40x (forty times greater) amount of blood flow to this area than to the brain. So it is the area with the highest blood flow in the entire body. 1) oxygen sensor: type 1 glomus cells.

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