01:146:328 Lecture Notes - Lecture 19: Antigenic Variation, Trypanosomatida, Tsetse Fly
27 Dec 2018
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Document Summary
28 november 2018: amastigote, promastigote, epimastigote, trypomastigote, order kinetoplastid, kinetoplast, basal body, major human infections, morphological forms, glycosome, genus trypanosoma. Section salivaria - trypanosoma brucei: section salivaria, section stercoraria, life cycle, 3 subspecies, glossina, t. brucei brucei, human african sleeping sickness, 2 subspecies, geographic distribution, disease, diagnosis, treatment, prevention and control. Section stercoraria: trypanosoma cruzi life cycle, trypomastigote, pathology, diagnosis, control, distribution, acute, asymptomatic, c hronic. Function: mitochondrial function / metamorphosis between life cycle forms. Associated with the outer surface of the mitochondrial membrane. Basal body and kinetoplast close together. What four morphological forms can occur in the various kinetoplastid life cycles: amastigote ld body, no flagellum, promastigote, flagellum locomotion and attachment, in insect vector, epimastigote, undulating membrane, in insect vector, trypomastigote. Stumpy in mammal, infective to insect. Metacyclic in insect, infective to mammal. Compartment surrounded by membrane in which many enzymes involved in glycolysis are located. Section salivaria is also known as anterior station development.
