01:146:328 Lecture Notes - Lecture 18: Entamoeba, Protozoa, Endosome
27 Dec 2018
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Document Summary
Commensals: live in humans but do not cause disease, why study, oro-fecal contamination, potential infection with pathogens, why identify, make correct diagnoses. Troph: 25 microns, lives in li, does not invade host tissue, nucleus large, eccentric endosome and irregularly clumped and dispersed peripheral chromatin. Cyst: ~17 microns, young, 1 divides to 2 divides to 4 nuclei, chromotoidal bars have splintered ends, mature cyst, 8 nuclei, chromotoidal bar disappeared, entomoeba gingivalis. In mouths of 95% of people with gum disease. In mouths of at least 50% with healthy gums. No evidence that it causes pathology: no cysts, trophozoite is the transmission stage, direct transmission kissing, indirect transmission utensils, morphology, similar to e. hystolytica, distinguish by habitat, endolimax nana. Trophozoites: ~ 8 microns, large, centric endosome, peripheral chromatin thin layer, slow moving. Cyst: 4 nuclei, ~ 6 microns, iodamoeba batschlii. Trophozoite: ~10 microns, large nucleus, eccentric endosome, chromatin is distributed as granules.
