01:146:328 Lecture Notes - Lecture 3: Trematode Life Cycle Stages, Schistosoma, Acetabulum

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:328
• Professor: Dr.Anne Keating

Document Summary

Strategy c: infect dh, cercaria transmission stage, migration in dh, development to adult worm, cercarial success. Morphology: head, escape exit snail, post acetabular mucus attachment to dh, pre acetabular enzymes help penetrate dh, head glands function in attachment to dh environment, tail. Schistosomula: can"t survive in water, inside dh, they get into bloodstream, migrate to lungs and live in pulmonary capillaries, where they grow and develop by feeing on red blood cells, then get into systemic circulation migrate through body call these young adults. Eggs must exit dh: adult worms, pair moves into smaller veins, female goes into smaller and smaller veins by herself (she is thinner, lays eggs, once she releases her eggs, she migrates back. Treatment: praziquantel, damages tegument causes immune response, effective on all 3 species, artemether, anti malarial drug, causes damage to the tegument of adult worms and cecum, some human trials look very promising.