01:146:328 Lecture Notes - Lecture 2: Liver Fluke, Hepatomegaly, Abdominal Wall
18 Mar 2016
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Diffusion goes down the concentration gradient, thus not wasting energy on this process: schistosome tegument is surrounded externally by lipid bilayer and internally by basal membrane, schistosome gtps are 2 types, sgtp1 located in basal membrane, sgtp4 located in the lipid bilayer. Embryonated eggs are discharged in the biliary ducts and in the stool. Eggs are ingested by a suitable snail (first intermediate host) Each egg releases a miracidia developmental stages (sporocysts. The cercariae are released from the snail and after a short period of free-swimming time in water, they come in contact and penetrate the flesh of freshwater fish (2nd ih), where they encyst as metacercariae. Infection of humans (dh) occurs by ingestion of undercooked, After ingestion, the salted, pickled, or smoked freshwater fish metacercariae excyst in the duodenum. 10 to 25 mm by 3 to 5 mm) reside in small and medium sized biliary ducts. In addition to humans, carnivorous animals can serve as reservoir hosts.
