01:146:356 Lecture Notes - Lecture 11: Digestion, Flow Measurement, Stroke Volume

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Systems Physiology Lecture 6 Notes: Regulation of Blood and Heart Rate
Total Blood Flow or Cardiac Output:
Q = ( dP r^4 ) / ( 8 n l )
Cardiac Output: the total volume of blood flow passing through either the
pulmonary or systemic circulations each minute
Q (or f = flow) = HR * Vs
Where Q= flow (mL/ min) , HR = heart rate (cpm), Vs= stroke volume (mL)
Measuig Q: Fik’s Piiple, flo poes, idiato-dilution techniques
Heart Rate can be affected by:
Temperature
Compounds in blood that build up
Chemical build up
Nerve input
Vs= stroke volume: volume of blood ejected into pulmonary/ aorta
(usually 60 t0 70 ml ejected)
Affected by:
Changing diastolic volume
Compliance of ventricles
Estimating the total blood flow:
Fik’s piiple s eletoagetic probes
Fik’s Piiple: if you a easue the uptake of O2 into pulmonary
arteries, then you can determine the necessary output of blood for
such an amount of O2 to be sufficiently circulated and the system to
be functioning properly
AVO2 Difference
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