01:160:308 Lecture Notes - Lecture 24: Solvation, Amine, Ketone
Document Summary
Chapter 23 amines: nomenclature, spectroscopic characteristics, basic strength of amines, synthesis of amines, reactions of amines. Amines can be classified as primary, secondary or tertiary. Iupac name: n-sub alkanamine, prefix name: n sub amino. Some common hetrocyclic amines, with common names (the n is normally considered to be numbered 1): Structure of amines: the nitrogen atom in an amine is sp3 hybridized -tetrahedral geometry molecular geometry - trigonal pyramidal. It is usually impossible to resolve amine enantiomers that are chiral at nitrogen because they interconvert rapidly. The interconversion occurs through a pyramidal inversion or nitrogen inversion involving the unshared electron pair: quaternary ammonium salts can be resolved into enantiomers. Chiral quaternary ammonium salts cannot undergo nitrogen inversion because they lack an unshared electron pair on the nitrogen atom. Ir: for primary amines two n-h stretches around 3400-3600 cm-1, for secondary just one n-h stretch, no n-h stretch for tertiary amines.
