11:216:101 Lecture Notes - Lecture 11: Last Glacial Maximum, Melanocortin 1 Receptor, Slc24A5

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Homo sapiens walked from asia to siberia, europe, Skull found from 125,000 - 105,00 years ago. Looks like eastern hmo neanderthalensis (only found in europe) Are we, homo sapiens, still undergoing natural selection changes. Melanin: dark skin- less photolysis, light skin- more photolysis. Vitamin d synthesis: making of vitamin d, 1st step occurs in the skin, vit. Sunlight: lighter will make more vitamin d when exposed to sunlight, we have low vitamin d indoors, sunscreen (prevent uv damage) 150,000 yrs homo sapiens in east africa, they were darker because they were out in the sun all the time. L- huge +++, easier to make vitamin d. Darker skin color pigmented h. sapiens walked out of africa-> europe, coast to east asia, D- yes, +++ very little vitamin d synthesis. L- huge +++, you can make more than someone darker. Skin color became lighter because low sunlight, cold weather (do not expose skin to sun)

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